Mekanism: Den fileöreslagna mekanismen är kompetitiv bindning av teofyllin till adenosinreceptorerna i hjärnan.
Särskilda populationer Äldre Diazepam 10 mg till salu i Sverige och försvagade patienter ska ges en reducerad dos (se avsnitt Dosering). På grund av den muskelavslappnande effekten finns det en possibility fileör tumble och därpå fileöljande höftfrakturer hos äldre patienter. En lägre dos rekommenderas även fileör patienter med kronisk respiratorisk insufficiens på grund av risken fileör andningsdepression. Bensodiazepiner är inte indicerade för behandling av patienter med svår leverinsufficiens eftersom läkemedlet kan påskynda encefalopati. Doseringen kan behöva reduceras hos patienter med kronisk leversjukdom. De normala fileörsiktighetsåtgärderna vid behandling av patienter med nedsatt njurfunktion ska beaktas.
Psychological reactions which include Excessive habits variations which include restlessness, agitation, or impulsivity
In equally untimely and comprehensive time period infants the Lively metabolite desmethyldiazepam reveals proof of continued accumulation compared to youngsters. extended fifty percent-life in infants may very well be as a result of incomplete maturation of metabolic pathways.
significant Unwanted effects which include coma and Dying have happened in Individuals who have abused or misused benzodiazepines, such as diazepam tablets. These major Unwanted side effects can also consist of delirium, paranoia, suicidal ideas or actions, seizures, and problems respiration.
Diazepam is applied to deal with panic, alcohol withdrawal, and seizures. It is usually employed To ease muscle mass spasms and to deliver sedation in advance of healthcare techniques. This medication functions by calming the Mind and nerves. Diazepam belongs to a class of medicines known as benzodiazepines.
Dosen måste reduceras för individer med cirros och fileörsämrad leverfunktion. Patienter med svårt fileörsämrad leverfunktion får inte behandlas med diazepam på grund av risken fileör leverencefalopati (se avsnitt Kontraindikationer).
Verkan: Dåsighet, minskad psykomotorisk förmåga och försämrat minne. Rekommendationen är att istället använda bensodiazepiner som metaboliseras genom icke-oxiderande vägar.
Concomitant usage of benzodiazepines and opioids may possibly result in profound sedation, respiratory melancholy, coma, and Demise. Reserve concomitant prescribing of such drugs in clients for whom choice remedy options are insufficient.
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great things about Klonopin Klonopin offers advantages that might make it a better choice than Valium or other benzodiazepines in some instances. it really works rather quickly, reaching its peak consequences inside a person to four several hours.
Samtidig användning av alkohol/CNS-dämpande läkemedel Samtidig användning av diazepam med alkohol och/eller CNS-dämpande läkemedel ska undvikas.
They might be Employed in clients with open up-angle glaucoma that are obtaining acceptable therapy, but are contraindicated in acute slender-angle glaucoma.
With newborn infants it has to be remembered the enzyme technique involved in the breakdown from the drug just isn't however thoroughly designed (specifically in untimely infants).